HERPES-SIMPLEX VIRUS TYPE-2 INFECTIONS PRESENTING AS BRAIN-STEM ENCEPHALITIS AND RECURRENT MYELITIS

被引：21

作者：

NAKAJIMA, H

FURUTAMA, D

KIMURA, F

SHINODA, K

NAKAGAWA, T

SHIMIZU, A

OHSAWA, N

机构：

[1] The First Department of Internal Medicine, Osaka Medical College, Osaka

[2] The Department of Clinical Pathology, Osaka Medical College, Osaka

来源：

INTERNAL MEDICINE | 1995年 / 34卷 / 09期

关键词：

POLYMERASE CHAIN REACTION; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID;

D O I：

10.2169/internalmedicine.34.839

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe here 3 patients with central nervous system infection caused by herpes simplex virus type 2 (HSV-2); one patient with brainstem encephalitis and two with recurrent transverse thoracic myelitis. All three patients showed increased IgG antibodies to HSV in the cerebrospinal fluid (CSF). HSV-2 DNA was demonstrated in the CSF by polymerase chain reaction (PCR) amplification. Upon treatment with acyclovir, one patient with myelitis partially recovered and the others completely recovered. It is important to recognize the wide spectrum of clinical manifestations of HSV-2 infection in the central nervous system (CNS).

引用

页码：839 / 842

页数：4

共 23 条

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