SSRIS IN ANXIOUS-AGITATED DEPRESSION - A POST-HOC ANALYSIS OF 279 PATIENTS

被引：32

作者：

FILTEAU, MJ

BARUCH, P

LAPIERRE, YD

BAKISH, D

BLANCHARD, A

机构：

[1] CTR RECH LAVAL ROBERT GIFFARD,BEAUPORT,PQ G1J 2G3,CANADA

[2] ROYAL OTTAWA HOSP,INST MENTAL HLTH RES,OTTAWA,ON K1Z 7K4,CANADA

来源：

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1995年 / 10卷 / 01期

关键词：

ANTIDEPRESSANTS; ANXIETY; DEPRESSION; SSRIS;

D O I：

10.1097/00004850-199503000-00007

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A post-hoc analysis of nine controlled antidepressant trials examined the intensity of the initial anxiety and agitation of depressed patients improved by SSRIs compared with depressed patients improved by norepinephrine (NE) reuptake inhibitors, mixed NE/serotonin reuptake inhibitors and placebo. We report that SSRI responders were more anxious-agitated than NE reuptake inhibitor responders, suggesting a preferential efficacy of SSRIs in agitated depression.

引用

页码：51 / 54

页数：4

共 19 条

[1] INTERACTING NEUROTRANSMITTER SYSTEMS - A NONEXPERIMENTAL APPROACH TO THE 5HIAA-HVA CORRELATION IN HUMAN CSF [J].

AGREN, H ;

MEFFORD, IN ;

RUDORFER, MV ;

LINNOILA, M ;

POTTER, WZ .

JOURNAL OF PSYCHIATRIC RESEARCH, 1986, 20 (03) :175-193

[2]

BALDWIN D, 1991, INT CLIN PSYCHOPHARM, V6, pS49

[3]

BEASLEY CM, 1991, J CLIN PSYCHOPHARM, V11, P166

[4]

BOYER WF, 1991, SELECTIVE SEROTONIN

[5]

COHN JB, 1992, J CLIN PSYCHIAT, V53, pS52

[6]

COLE JO, 1967, COMPREHENSIVE TXB PS, P1263

[7]

DELIA G, 1981, ACTA PSYCHIAT SCAND, V63, pS225

[8] THE ANTIANXIETY AND ANTIAGITATION EFFECTS OF PAROXETINE IN DEPRESSED-PATIENTS [J].

DUNBAR, GC ;

FUELL, DL .

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 1992, 6 :81-90

[9]

GORMAN JM, 1987, J CLIN PSYCHOPHARM, V7, P329

[10]

HAMILTON M, 1988, HDB ANXIETY DISORDER

← 1 2 →