R1128 SUBSTANCES, NOVEL NONSTEROIDAL ESTROGEN-RECEPTOR ANTAGONISTS PRODUCED BY A STREPTOMYCES .2. PHYSICOCHEMICAL PROPERTIES AND STRUCTURE DETERMINATION

被引：17

作者：

HORI, Y

TAKASE, S

SHIGEMATSU, N

GOTO, T

OKUHARA, M

KOHSAKA, M

机构：

[1] Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki,300-26, 5-2-3 Tokodai, Tsukuba

来源：

JOURNAL OF ANTIBIOTICS | 1993年 / 46卷 / 07期

关键词：

D O I：

10.7164/antibiotics.46.1063

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

R1128 A, B, C and D, new non-steroidal estrogen-receptor antagonists, were isolated from the cultured broth of Streptomyces sp. No. 1128. Their structures were elucidated to be 1,3,6-trihydroxy-8-alkylanthraquinones on the basis of their physico-chemical properties and spectroscopic data.

引用

页码：1063 / 1068

页数：6

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