THE GAMMA-HEMOLYSIN LOCUS OF STAPHYLOCOCCUS-AUREUS COMPRISES 3 LINKED GENES, 2 OF WHICH ARE IDENTICAL TO THE GENES FOR THE F AND S COMPONENTS OF LEUKOCIDIN

被引：79

作者：

COONEY, J

KIENLE, Z

FOSTER, TJ

OTOOLE, PW

机构：

[1] UNIV LUND,DEPT MED & PHYSIOL CHEM,S-21401 MALMO,SWEDEN

[2] UNIV LUND,DEPT MED MICROBIOL,S-21401 MALMO,SWEDEN

[3] UNIV DUBLIN TRINITY COLL,DEPT MICROBIOL,MOYNE INST,DUBLIN 2,IRELAND

来源：

INFECTION AND IMMUNITY | 1993年 / 61卷 / 02期

关键词：

D O I：

10.1128/IAI.61.2.768-771.1993

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The Staphylococcus aureus gamma-hemolysin comprises two polypeptides, whereas the gamma-hemolysin locus (hlg) contains three open reading frames. The hlgA and hlgB genes encode the gamma1 and gamma2 components, respectively. The HlgB protein (gamma2) has 27% residue identity with S. aureus alpha-toxin. Surprisingly, hlgB and hlgC are 98.5 and 99.1% identical to the lukF and lukS genes, respectively, encoding the F and S components of the Panton-Valentine leukocidin.

引用

页码：768 / 771

页数：4

共 14 条

[1] CHARACTERIZATION OF STAPHYLOCOCCAL GAMMA-LYSIN
CLYNE, M
BIRKBECK, TH
ARBUTHNOTT, JP
[J]. JOURNAL OF GENERAL MICROBIOLOGY, 1992, 138 : 923 - 930
[2] COONEY J, 1988, J GEN MICROBIOL, V134, P2179
[3] A COMPREHENSIVE SET OF SEQUENCE-ANALYSIS PROGRAMS FOR THE VAX
DEVEREUX, J
HAEBERLI, P
SMITHIES, O
[J]. NUCLEIC ACIDS RESEARCH, 1984, 12 (01) : 387 - 395
[4] Foster T. J., 1990, MOL BIOL STAPHYLOCOC, P403
[5] GUYONNET F, 1970, ANN I PASTEUR PARIS, V118, P19
[6] GUYONNET F, 1968, CR ACAD SCI D NAT, V267, P1180
[7] RAPID DETECTION OF HELICOBACTER-PYLORI IN GASTRIC BIOPSY MATERIAL BY POLYMERASE CHAIN-REACTION
HAMMAR, M
TYSZKIEWICZ, T
WADSTROM, T
OTOOLE, PW
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (01) : 54 - 58
[8] HIGGINS DG, 1989, COMPUT APPL BIOSCI, V5, P151
[9] MOLLBY R, 1983, STAPHYLOCOCCI STAPHY, V2, P619
[10] CRYSTALLIZATION AND PROPERTIES OF STAPHYLOCOCCAL LEUKOCIDIN
NODA, M
HIRAYAMA, T
KATO, I
MATSUDA, F
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1980, 633 (01) : 33 - 44

← 1 2 →