SUPERANTIGENS IN KAWASAKI SYNDROME

被引：22

作者：

LEUNG, DYM

MEISSNER, HC

FULTON, DR

QUIMBY, F

SCHLIEVERT, PM

机构：

[1] UNIV COLORADO, HLTH SCI CTR, DEPT PEDIAT, DENVER, CO 80262 USA

[2] TUFTS UNIV NEW ENGLAND MED CTR, DEPT PEDIAT, BOSTON, MA 02111 USA

[3] CORNELL UNIV, COLL VET, ITHACA, NY 14853 USA

[4] UNIV MINNESOTA, DEPT MICROBIOL, MINNEAPOLIS, MN 55455 USA

来源：

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY | 1995年 / 77卷 / 02期

关键词：

D O I：

10.1006/clin.1995.1134

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Kawasaki syndrome (KS) is an acute multisystem vasculitis of infancy and early childhood associated with the development of myocarditis and coronary artery abnormalities. Despite the widely held belief that KS is caused by an infectious agent, there remains considerable controversy over its etiology. Recent immunologic and microbiologic studies suggest a potential role for staphylococcal and streptococcal toxins (superantigens) in the pathogenesis of KS. Confirmation of these findings could result in more effective diagnostic and therapeutic approaches to this common cause of acquired heart disease in children. (C) 1995 Academic Press, Inc.

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页码：119 / 126

页数：8

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