DETERMINATION OF IONOPHORES IN THE TISSUES OF FOOD ANIMALS BY LIQUID-CHROMATOGRAPHY

被引：29

作者：

GERHARDT, GC

SALISBURY, CDC

CAMPBELL, HM

机构：

[1] Health of Animals Laboratory, Agriculture and Agri-Food Canada, Saskatoon, SK, S7N 2R3

[2] Feed and Fertilizer Laboratory, Laboratory Services Division, Agriculture and Agri-Food Canada, Ottawa, ON, KIA 0C6, Building No. 22, Central Experimental Farm

来源：

FOOD ADDITIVES AND CONTAMINANTS | 1995年 / 12卷 / 06期

关键词：

IONOPHORES; LASALOCID; SALINOMYCIN; NARASIN; MONENSIN;

D O I：

10.1080/02652039509374365

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A liquid chromatographic method for determining residues of ionophores in bovine, porcine, and avian tissues is described. Tissues were extracted with iso-octane-ethyl acetate and the extracts purified on silica solid-phase extraction columns. Monensin, narasin and salinomycin were detected by UV absorbance following post-column derivatization with vanillin, and lasalocid was detected underivatized using fluorescence. In muscle, kidney and far, all drugs were determined from a single sample extract. In liver, a separate extraction was done to determine lasalocid. The detection limit for lasalocid, narasin and salinomycin was 5 ppb; for monensin it was 2 ppb. Average recoveries were: lasalocid-71.0%; monensin-94.3%; salinomycin-97.2%; narasin-94.1%.

引用

页码：731 / 737

页数：7

共 14 条

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