STUDY ON THERMOSTABILIZERS FOR TRIVALENT ORAL POLIOMYELITIS VACCINE

被引：2

作者：

LEAL, MLF

LOPES, FJC

CARVALHO, MHG

MOURA, HAB

SOARES, SAF

机构：

[1] Fundação Oswaldo Cruz, Depro, Brasil, Rio de Janeiro

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 1990年 / 85卷 / 03期

关键词：

D O I：

10.1590/S0074-02761990000300010

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Different formulations of Trivalent Oral Poliomyelitis Vaccine were tested, in order to obtain better thermostability, reduce corrosion of machinery and improve production costs. Magnesium chloride, sucrose, arginine and 199-Hank's medium were used in the formulations. The most appropriate formulation was a mixture of MgCl2 and arginine, which was highly thermostable, and had low production costs.

引用

页码：329 / 338

页数：10

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