IMPORTANCE OF COMPRESSION ONSET RATE FOR THE DEGREE OF IMPAIRMENT OF IMPULSE PROPAGATION IN EXPERIMENTAL COMPRESSION INJURY OF THE PORCINE CAUDA-EQUINA

被引:57
作者
OLMARKER, K
HOLM, S
RYDEVIK, B
机构
[1] Laboratory of Experimental Biology, Department of Anatomy, Gothenburg University, Gothenburg
[2] Department of Orthopaedics, Sahlgren Hospital, Gothenburg University, Gothenburg
关键词
Compression; Edema; Nerve function; Nerve roots; Onset rate;
D O I
10.1097/00007632-199005000-00013
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The effects of a rapid (0.05-0.1 seconds) and a slow (20 seconds) onset rate of cauda equina compression on impulse propagation, in terms of tail muscle electromyogram (EMG) amplitude, were analyzed in an experimental model of the pig cauda equina. Sham compression and compression at 50 mm Hg at either rapid or slow onset induced no or only minor functional impairment. Compression at 100 or 200 mm Hg induced impairment of the impulse propagation that was proportional to the applied pressure. The effects were more pronounced (P < 0.01) for the rapid than for the slow onset of compression at both these pressure levels. An important factor for this observed difference in effects between the two employed onset rates seems to be the magnitude of intraneural edema formed outside the compression zone. © Lippincott-Raven Publishers.
引用
收藏
页码:416 / 419
页数:4
相关论文
共 14 条
[1]  
Low P.A., Dyck P.J., Increased endoneurial fluid pressure in experimental lead neuropathy, Nature, 269, pp. 427-428, (1977)
[2]  
Low P.A., Dyck P.J., Schmelzer J.D., Chronic elevation of endoneurial fluid pressure is associated with low-grade fiber pathology, Muscle Nerve, 5, pp. 162-165, (1982)
[3]  
Lundborg G., Myers R., Powell H., : Nerve compression injury and increased endoneurial fluid pressure: A “miniature compartment syndrome, J Neurol Neurosurg Psychiatry, 46, pp. 1119-1124, (1983)
[4]  
Macgregor R.J., Sharpless S.K., Luttges M.W., A pressure vessel model for nerve compression, J Neurol Sci, 24, pp. 299-304, (1975)
[5]  
Myers R.R., Mizisin A.P., Powell H.C., Lampert P.W., Reduced nerve blood flow in hexachlorophene neuropathy. Relationship to elevated endoneurial fluid pressure, J Neuropathol Exp Neurol, 41, pp. 391-399, (1982)
[6]  
Ochoa J., Fowler T.J., Gilliat R.W., Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet, J Anat, 113, pp. 433-455, (1972)
[7]  
Olmarkcr K., Rydevik B., Holm S., Edema formation in spinal nerve roots induced by experimental, graded compression. An experimental study on the pig cauda equina with Special reference to differences in effects between rapid and slow onset of compression, Spine, 14, pp. 569-573, (1989)
[8]  
Olmarker K., Rydevik B., Holm S., Bagge U., Effects of experimental, graded compression on blood flow in spinal nerve roots, A Vital Microscopic Study on the Porcine Cauda Equina. J Orthop Res, (1989)
[9]  
Olmarker K., Rydevik B., Hansson T., Holm S., Compression-induced changes of the nutritional supply to the porcine cauda equina, Manuscript, (1989)
[10]  
Pedowitz R.A., Garfin S.R., Hargens A.R., Et al., Effects of magnitude and duration of compression on spinal nerve root conduction, Manuscript, (1989)