STEADY MAGNETIC-FIELDS EFFECT ON LIPID-PEROXIDATION KINETICS

被引：23

作者：

LALO, UV ^{[1
]}

PANKRATOV, YV ^{[1
]}

MIKHAILIK, OM ^{[1
]}

机构：

[1] SCI ENGN CTR BIOTECH SYST,SONAR,KIEV 252057,UKRAINE

来源：

REDOX REPORT | 1994年 / 1卷 / 01期

关键词：

D O I：

10.1080/13510002.1994.11746959

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effect of steady magnetic fields (ranging from 0 to 280 mT) has been investigated on the kinetics of non-enzymatic lipid peroxidation occurring in a model system consisting of liposomes obtained from 1,2-dioleoylphosphatidylcholine by oxygen consumption. The process was found to be accelerated by weak steady magnetic fields, A computer simulation method was employed to detect the reactions that govern the process kinetics, to elucidate magneto-sensitive stages (initiation and reduction of iron(III), as well as lipid peroxide radical recombination) and to determine their rate constants at various external magnetic fields, The kinetics of peroxidation of lipid cell membranes have been modeled mathematically at oxygen and 'free' iron concentrations close to those in the cells and also at increased free iron concentrations at different external magnetic field values.

引用

页码：71 / 75

页数：5

共 18 条

[1] DIFFUSION OF UNIVALENT IONS ACROSS LAMELLAE OF SWOLLEN PHOSPHOLIPIDS [J].