THE LANGAT MODEL FOR TICK-BORNE ENCEPHALITIS-VIRUS - SPECIFIC DETECTION BY RT-PCR

被引：6

作者：

CAMPBELL, J

IACONOCONNORS, L

WALZ, S

SCHULTZ, W

机构：

[1] USN,RES LAB,CTR BIOMOLEC SCI,CODE 6900,WASHINGTON,DC 20375

[2] USA,MED RES INST INFECT DIS,FREDERICK,MD 21701

来源：

JOURNAL OF VIROLOGICAL METHODS | 1993年 / 44卷 / 2-3期

关键词：

LANGAT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TICK-BORNE ENCEPHALITIS;

D O I：

10.1016/0166-0934(93)90058-Y

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have developed a reverse-transcriptase polymerase chain reaction assay for rapid detection of Langat (LGT) virus, a flavivirus that is closely related to the highly pathogenic tick-borne encephalitis (TBE) viruses. Unlike TBE viruses, LGT virus exhibits a significantly lower virulence for man. The assay serves as a safe alternative for the development and optimization of specific assays for the highly pathogenic subtypes of TBE viruses that are endemic throughout much of Europe, the former Soviet Union, and China.

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页码：235 / 240

页数：6

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