Heterotrimeric G-protein signaling in Arabidopsis

被引:9
作者
Chen, Jin-Gui [1 ]
机构
[1] Univ British Columbia, Dept Bot, Vancouver, BC V6T 1Z4, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
heterotrimeric G-proteins; GCR2; GPA1; G-protein-coupled receptor (GPCR); AtRGS1;
D O I
10.4161/psb.3.12.6064
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Seven transmembrane G-protein-coupled receptors (GPCRs) are commonly used by eukaryotes to sense extracellular signals to switch on cellular responses through the activation of cognate heterotrimeric G-proteins. In Arabidopsis thaliana, GCR2 has been proposed as a GPCR for the plant hormone abscisic acid. On the other hand, biochemical analysis demonstrates that the sole Arabidopsis heterotrimeric G-protein a subunit, GPA1, is in the activated state (GTP-bound) by default, suggesting that the heterotrimeric G-proteins may act without any GPCRs.
引用
收藏
页码:1042 / 1045
页数:4
相关论文
共 21 条
[1]  
Adjobo Hermans MJ, 2006, J CELL SCI, V119, P5087
[2]   Heterotrimeric and unconventional GTP binding proteins in plant cell signaling [J].
Assmann, SM .
PLANT CELL, 2002, 14 (SUPPL.) :S355-S373
[3]  
ASSMANN SM, 2005, SCI STKE
[4]   Signaling at zero G: G-protein-independent functions for 7-TM receptors [J].
Brzostowski, JA ;
Kimmel, AR .
TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (05) :291-297
[5]   GCR1 can act independently of heterotrimeric G-protein in response to brassinosteroids and gibberellins in Arabidopsis seed germination [J].
Chen, JG ;
Pandey, S ;
Huang, JR ;
Alonso, JM ;
Ecker, JR ;
Assmann, SM ;
Jones, AM .
PLANT PHYSIOLOGY, 2004, 135 (02) :907-915
[6]   A seven-transmembrane RGS protein that modulates plant cell proliferation [J].
Chen, JG ;
Willard, FS ;
Huang, J ;
Liang, JS ;
Chasse, SA ;
Jones, AM ;
Siderovski, DP .
SCIENCE, 2003, 301 (5640) :1728-1731
[7]   Plant hormone receptors: perception is everything [J].
Chow, Brenda ;
McCourt, Peter .
GENES & DEVELOPMENT, 2006, 20 (15) :1998-2008
[8]   Genetic characterization reveals no role for the reported ABA receptor, GCR2, in ABA control of seed germination and early seedling development in Arabidopsis [J].
Gao, Yajun ;
Zeng, Qingning ;
Guo, Jianjun ;
Cheng, Jia ;
Ellis, Brian E. ;
Chen, Jin-Gui .
PLANT JOURNAL, 2007, 52 (06) :1001-1013
[9]   Criteria for confirming sequence periodicity identified by Fourier transform analysis: Application to GCR2, a candidate plant GPCR? [J].
Illingworth, Christopher J. R. ;
Parkes, Kevin E. ;
Snell, Christopher R. ;
Mullineaux, Philip M. ;
Reynolds, Christopher A. .
BIOPHYSICAL CHEMISTRY, 2008, 133 (1-3) :28-35
[10]   Comment on "A G protein-coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid" [J].
Johnston, Christopher A. ;
Temple, Brenda R. ;
Chen, Jin-Gui ;
Gao, Yajun ;
Moriyama, Etsuko N. ;
Jones, Alan M. ;
Siderovski, David P. ;
Willard, Francis S. .
SCIENCE, 2007, 318 (5852) :914c