REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY FOR THE DETERMINATION OF STEROID-HORMONES IN ORAL-CONTRACEPTIVES

被引：14

作者：

BOND, AM ^{[1
]}

HERITAGE, ID ^{[1
]}

BRIGGS, MH ^{[1
]}

机构：

[1] DEAKIN UNIV, DIV BIOL & HLTH SCI, GEELONG, VIC 3217, AUSTRALIA

来源：

JOURNAL OF CHROMATOGRAPHY | 1984年 / 315卷 / DEC期

关键词：

D O I：

10.1016/S0021-9673(01)90748-4

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Reversed-phase high-performance liquid chromatography with UV detection was studied for the determination of both progestogenic and estrogenic components of oral contraceptive formulations. The applicability of the assay was demonstrated for a number of different progestogen-estrogen combinations in both conventional tablet and novel paper formulations. The method developed was a versatile technique for the routine assay of these pharmaceutical formulations.

引用

页码：313 / 320

页数：8

共 11 条

[1] DETERMINATION OF ETHINYLESTRADIOL IN SINGLE TABLETS AND ITS SEPARATION FROM OTHER STEROIDS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

BAGON, KR ;

HAMMOND, EW .

ANALYST, 1978, 103 (1223) :156-161

[2]

GOROG S, 1978, ANAL STEROID HORMONE, P372

[3] HIGH-PRESSURE LIQUID-CHROMATOGRAPHY OF STEROIDS [J].

HEFTMANN, E ;

HUNTER, IR .

JOURNAL OF CHROMATOGRAPHY, 1979, 165 (03) :283-299

[4] FLUOROMETRIC-DETERMINATION OF ETHINYL ESTRADIOL IN TABLETS [J].

JAMES, T .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (08) :1306-&

[5]

JOHNSTON MA, 1981, J CHROMATOGR, V216, P269

[6]

KAUTSKY M, 1980, CHROMATOGRAPHIC SCI, V16

[7] USE OF ORGANIC MODIFIERS IN THE MOBILE PHASE FOR THE REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF STEROIDAL HORMONES [J].

LEE, GJL ;

CARLSON, RMK ;

KUSHINSKY, S .

JOURNAL OF CHROMATOGRAPHY, 1981, 212 (01) :108-114

[8]

MILLER JHM, 1976, P ANAL DIV CHEM SOC, V13, P93

[9] ROLE OF ORGANIC MODIFIERS ON POLAR GROUP SELECTIVITY IN REVERSED-PHASE LIQUID-CHROMATOGRAPHY [J].

TANAKA, N ;

GOODELL, H ;

KARGER, BL .

JOURNAL OF CHROMATOGRAPHY, 1978, 158 (OCT) :233-248

[10] COMPARATIVE STUDY OF A NEW FLUOROMETRIC ASSAY MESTRANOL ETHER IN TABLETS WITH GLC AND COLORIMETRIC ASSAYS [J].

TEMPLETON, RJ ;

ARNETT, WA ;

JAKOVLJEVIC, IM .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1968, 57 (07) :1168-+

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