INTERCORRELATIONS AMONG MONOAMINE METABOLITE CONCENTRATIONS IN HUMAN LUMBAR CSF ARE NOT DUE TO A SHARED ACID TRANSPORT-SYSTEM

被引：22

作者：

JIBSON, M

FAULL, KF

CSERNANSKY, JG

机构：

[1] STANFORD UNIV,MED CTR,SCH MED,DEPT PSYCHIAT & BEHAV SCI,STANFORD,CA 94305

[2] VET ADM MED CTR,PALO ALTO,CA 94304

来源：

BIOLOGICAL PSYCHIATRY | 1990年 / 28卷 / 07期

关键词：

D O I：

10.1016/0006-3223(90)90397-K

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Intercorrelations among homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and 3-methoxy-hydroxy-phenylglycol (MHPG) concentrations in lumbar cerebrospinal fluid (CSF) were examined before and after blockade of the acid transport system by probenecid in 59 psychiatric inpatients. The three compounds remained intercorrelated despite acid transport blockade, suggesting that the common transport system does not account for their covariance. Other possibilities to explain the interrelationship among these compounds are discussed. © 1990.

引用

页码：595 / 602

页数：8

共 39 条

[1] INTERACTING NEUROTRANSMITTER SYSTEMS - A NONEXPERIMENTAL APPROACH TO THE 5HIAA-HVA CORRELATION IN HUMAN CSF [J].