A CONVENIENT SYNTHESIS OF BRIDGED AZATRICYCLIC ANHYDRIDES

被引：19

作者：

CANONNE, P

AKSSIRA, M

DAHDOUH, A

KASMI, H

BOUMZEBRA, M

机构：

[1] UNIV ABDELMALEK ESSAADI,FAC SCI,DEPT CHIM,CHIM ORGAN LAB,BP 2121,TETOUAN,MOROCCO

[2] UNIV LAVAL,DEPT COMPREHENS CANC,QUEBEC CITY G1K 7P4,QUEBEC,CANADA

来源：

TETRAHEDRON | 1993年 / 49卷 / 10期

关键词：

D O I：

10.1016/S0040-4020(01)86298-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bridged N-protected beta-amino acids have been regioselectively prepared from the corresponding bicyclic monoesters. The subsequent cyclisation by thionyl chloride produced the desired bridged azatricyclic anhydrides which are versatile substrates for the synthesis of dipeptides; they are also converted into oxathymine and oxauracil by a thermal [4 + 2] cycloreversion.

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页码：1985 / 1992

页数：8

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