BLEOMYCIN THERAPY FOR CYSTIC HYGROMA

被引:113
作者
ORFORD, J [1 ]
BARKER, A [1 ]
THONELL, S [1 ]
KING, P [1 ]
MURPHY, J [1 ]
机构
[1] PRINCESS MARGARET HOSP CHILDREN,DIV SURG,SUBIACO,WA 6008,AUSTRALIA
关键词
CYSTIC HYGROMA; LYMPHANGIOMA; SCLEROSING THERAPY; BLEOMYCIN;
D O I
10.1016/0022-3468(95)90485-9
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Intralesional bleomycin injection was used as sclerosant therapy for sixteen patients with cystic hygroma. An excellent (complete clinical resolution) response was obtained in seven (44%) patients, a good (> 50% response) result in seven (44%), and a poor or no response in two (12%). Minor transient side effects (fever, vomiting, cellulitis, skin discoloration) were seen in six patients, and there were no serious side effects. The results suggest that bleomycin intralesional sclerosant is effective therapy for cystic hygroma, with response rates comparable to those of surgical removal, but with the advantage of avoiding inadvertent nerve damage and scarring. Copyright (C) 1995 by W.B. Saunders Company.
引用
收藏
页码:1282 / 1287
页数:6
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