ON THE USE OF SILYLATED NUCLEOPHILES IN THE PALLADIUM CATALYZED DEPROTECTION OF ALLYLIC CARBOXYLATES AND CARBAMATES

被引：52

作者：

MERZOUK, A

GUIBE, F

LOFFET, A

机构：

[1] UNIV PARIS 11,CNRS,INST CHIM MOLEC ORSAY,CHIM ORGAN ELEMENTS TRANSIT LAB,BAT 420,F-91405 ORSAY,FRANCE

[2] PROPEPTIDE,F-91710 VERT LE PETIT,FRANCE

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 04期

关键词：

ALLYLOXYCARBONYL PROTECTIVE GROUP; SILYLAMINES; PALLADIUM CATALYSIS; AMINO-ACIDS PROTECTION; PROTECTIVE GROUP CHEMISTRY;

D O I：

10.1016/S0040-4039(00)93973-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium catalysed cleavage of allylic esters by silylated amines such as trimethylsilyldimethylamine or trimethylsilylmorpholine (sometimes used in association with an electrophilic silylating agent such as trimethylsily acetate) allows the deprotection of allylic carbamates under very mild, selective, and easy to work conditions.

引用

页码：477 / 480

页数：4

共 14 条

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