A STUDY OF THE INTERFACE BETWEEN A FIBROUS POLYURETHANE ARTERIAL PROSTHESIS AND NATURAL TISSUE

被引：12

作者：

BEAHAN, P

HULL, D

机构：

[1] Dep. Metall. Mater. Sci., Univ. Liverpool, Liverpool L693BX, United Kingdom

来源：

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1982年 / 16卷 / 06期

关键词：

BIOLOGICAL MATERIALS - Tissue - BIOMEDICAL ENGINEERING - Surgical Implants - FIBERS; NONTEXTILE - Medical Applications - POLYURETHANES - Biocompatibility - TUBES - Forming;

D O I：

10.1002/jbm.820160608

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Fibrous polyurethane samples were implanted in minipigs in subcutaneous tissue, muscle, and as an arterial prosthesis for periods up to six months. The interface between the polymer and living tissue was studied using optical, scanning, and transmission electron microscopy. A good correlation was found between the micromorphology of the polymer-tissue interface observed in three experimental methods used. Ingrowth of tissue occurs by cell penetration into the fibrous network of the polymer implant and eventual encapsulation by connective tissue. Full details of the distribution of collagen and the cell components around the individual polymer fibers and the structure of the connective tissue are given.

引用

页码：827 / 838

页数：12

共 12 条

[1]

ANNIS D, 1978, T AM SOC ART INT ORG, V24, P209

[2] THE USE OF TUBES CONSTRUCTED FROM VINYON N-CLOTH IN BRIDGING ARTERIAL DEFECTS - EXPERIMENTAL AND CLINICAL [J].