MULTIPLE UNRELATED CHROMOSOME-ABNORMALITIES IN A METASTATIC MUCOEPIDERMOID CARCINOMA OF THE PAROTID-GLAND

被引：14

作者：

NORDKVIST, A

EDSTROM, S

MARK, J

STENMAN, G

机构：

[1] UNIV GOTEBORG,DEPT ORAL PATHOL,CYTOGENET LAB,MED GATAN 12,S-41390 GOTHENBURG,SWEDEN

[2] GOTHENBURG UNIV,DEPT OTORHINOLARYNGOL,S-41124 GOTHENBURG,SWEDEN

[3] CENT HOSP SKOVDE,DEPT PATHOL,SKOVDE,SWEDEN

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 61卷 / 02期

关键词：

D O I：

10.1016/0165-4608(92)90080-R

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We describe cytogenetic findings in a poorly differentiated, metastatic mucoepidermoid carcinoma of the parotid gland. The tumor was characterized by multiple, unrelated chromosome abnormalities. Except for two small aberrant clones showing t(1;7) and t(2;15), respectively, all other abnormal cells showed unique, mostly structural rearrangements peculiar to each cell. No less than 34 different abnormal karyotypes were observed. A similar karyotypic heterogeneity was also described recently in squamous cell carcinomas of the head and neck.

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页码：158 / 161

页数：4

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