EFFECT OF LANTHANUM IONS ON THE RELEASE OF ACETYLCHOLINE-INDUCED BY TITYUSTOXIN, K+ AND OUABAIN FROM MYENTERIC PLEXUS AND BRAIN CORTICAL SLICES

被引：5

作者：

GOMEZ, RS

MORAESSANTOS, T

GOMEZ, MV

机构：

[1] UFMG,INST CIENCIAS BIOL,DEPT FARMACOL,BR-2486 BELO HORIZON,MG,BRAZIL

[2] UFMG,FAC FARM,DEPT ALIMENTOS,BR-3000 BELO HORIZON,MG,BRAZIL

来源：

TOXICON | 1993年 / 31卷 / 04期

关键词：

D O I：

10.1016/0041-0101(93)90176-J

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Exposure of myenteric plexus longitudinal muscles to 2 mM LaCl3 increased the rate of spontaneous [H-3]-ACh release. In brain cortical slices La3+ did not affect the spontaneous release of ACh. The release of ACh induced by tityustoxin, ouabain or K+ 50 mM in brain cortex and myenteric longtudinal muscles slices was inhibited by La3+ treatment. It is suggested that tityustoxin, ouabain and K+ release ACh from the same pool that is inhibited by La3+ pretreatment.

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收藏

页码：411 / 415

页数：5

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