METHANESULFENYL TRIFLATE PROMOTED IMINOSULFENYLATION OF AN ALLYLIC TRICHLOROACETIMIDATE - AN EFFICIENT AND STEREOSPECIFIC TOTAL SYNTHESIS OF (+)-MANNOSTATIN-A

被引：24

作者：

LI, C ^{[1
]}

FUCHS, PL ^{[1
]}

机构：

[1] PURDUE UNIV,DEPT CHEM,W LAFAYETTE,IN 47907

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 29期

关键词：

D O I：

10.1016/S0040-4039(00)77043-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereospecific synthesis of glycoprotein processing enzyme inhibitor (+) mannostatin A 1 was achieved in ten steps from D-ribonolactone 9 (similar to 39% overall yield). The strategy featured methanesulfenyl triflate mediated intramolecular cyclization of allylic N-sufenylimidate 12.

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页码：5121 / 5124

页数：4

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