MOLECULAR MECHANISMS OF CALCIUM-INDUCED MEMBRANE-FUSION

被引：198

作者：

PAPAHADJOPOULOS, D

NIR, S

DUZGUNES, N

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACOL,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

[3] HEBREW UNIV JERUSALEM,FAC AGR,SEAGRAM CTR,IL-76100 REHOVOT,ISRAEL

来源：

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES | 1990年 / 22卷 / 02期

关键词：

annexins; calcium; calcium-binding-proteins; lipid-bilayer; Liposomes; membrane-fusion; model-membranes;

D O I：

10.1007/BF00762944

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We have reviewed studies on calcium-induced fusion of lipid bilayer membranes and the role of synexin and other calcium-binding proteins (annexins) in membrane fusion. We have also discussed the roles of other cations, lipid phase transitions, long chain fatty acids and other fusogenic molecules. Finally, we have presented a simple molecular model for the mechanism of lipid membrane fusion, consistent with the experimental evidence and incorporating various elements proposed previously. © 1990 Plenum Publishing Corporation.

引用

页码：157 / 179

页数：23

共 159 条

[1] FUSION OF ERYTHROCYTES BY FATTY-ACIDS, ESTERS, RETINOL AND ALPHA-TOCOPHEROL [J].