LIGHT-INDUCED DNA CLEAVAGE BY BIS-9-ACRIDINYL VIOLOGEN DERIVATIVE

被引:20
作者
TAKENAKA, S [1 ]
IHARA, T [1 ]
TAKAGI, M [1 ]
机构
[1] KYUSHU INST TECHNOL, FAC COMP SCI & SYST ENGN, DEPT BIOCHEM ENGN & SCI, KAWAZU, IIZUKA 820, JAPAN
关键词
D O I
10.1246/cl.1992.1
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A bis-9-acridinyl derivative containing a viologen linker chain (3) forms an intercalation complex with DNA, and was found to cleave the double chain DNA strand effectively under irradiation by visible light, due to the photosensitized intramolecular electron transfer from the acridine to viologen moieties within 3.
引用
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页码:1 / 4
页数:4
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