TREATMENT OF OLD-WORLD CUTANEOUS LEISHMANIASIS WITH AMINOSIDINE OINTMENT - RESULTS OF AN OPEN STUDY IN LONDON

被引：45

作者：

BRYCESON, ADM ^{[1
]}

MURPHY, A ^{[1
]}

MOODY, AH ^{[1
]}

机构：

[1] UCL HOSP, DEPT PHARM, LONDON WC1E 6AU, ENGLAND

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1994年 / 88卷 / 02期

关键词：

D O I：

10.1016/0035-9203(94)90308-5

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Five preparations of ointment containing aminosidine were used to treat lesions of 'Old World' cutaneous leishmaniasis. A preparation containing 12-15% aminosidine with 10% urea in white soft paraffin was nontoxic. 23 of 27 patients treated healed in a mean of 6.7 weeks, the ointment being applied daily for up to 12 weeks.

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页码：226 / 228

页数：3

相关论文

共 12 条

[1]

AKOVBYAN AA, 1968, TROP DIS B, V65, P987

[2] TREATMENT OF VISCERAL LEISHMANIASIS IN KENYA BY AMINOSIDINE ALONE OR COMBINED WITH SODIUM STIBOGLUCONATE [J].

CHUNGE, CN ;

OWATE, J ;

PAMBA, HO ;

DONNO, L .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1990, 84 (02) :221-225

[3] A DOUBLE-BLIND-STUDY ON THE EFFICACY OF ORAL DAPSONE IN CUTANEOUS LEISHMANIASIS [J].

DOGRA, J .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1991, 85 (02) :212-213

[4] TOPICAL TREATMENT OF OLD-WORLD CUTANEOUS LEISHMANIASIS CAUSED BY LEISHMANIA-MAJOR - A DOUBLE-BLIND CONTROL STUDY [J].

ELON, J ;

HALEVY, S ;

GRUNWALD, MH ;

WEINRAUCH, L .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1992, 27 (02) :227-231

[5] TOPICAL TREATMENT OF CUTANEOUS LEISHMANIASIS [J].

ELON, J ;

LIVSHIN, R ;

EVENPAZ, Z ;

HAMBURGER, D ;

WEINRAUCH, L .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1986, 87 (02) :284-288

[6] DEVELOPMENT OF TOPICAL TREATMENT FOR CUTANEOUS LEISHMANIASIS CAUSED BY LEISHMANIA-MAJOR IN EXPERIMENTAL-ANIMALS [J].

ELON, J ;

JACOBS, GP ;

WITZTUM, E ;

GREENBLATT, CL .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1984, 26 (05) :745-751

[7] LEISHMANIA-MAJOR - ANTILEISHMANIAL ACTIVITY OF METHYLBENZETHONIUM CHLORIDE [J].

ELON, J ;

MESSER, G .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1986, 35 (06) :1110-1116

[8] A DOUBLE-BLIND CLINICAL-TRIAL OF THE TREATMENT OF CUTANEOUS LEISHMANIASIS WITH PAROMOMYCIN OINTMENT [J].

ELSAFI, SH ;

MURPHY, AG ;

BRYCESON, ADM ;

NEAL, RA .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1990, 84 (05) :690-691

[9] ALLOPURINOL IN THE TREATMENT OF AMERICAN CUTANEOUS LEISHMANIASIS [J].

MARTINEZ, S ;

MARR, JJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (11) :741-744

[10] PLACEBO-CONTROLLED CLINICAL-TRIAL OF SODIUM STIBOGLUCONATE (PENTOSTAM) VERSUS KETOCONAZOLE FOR TREATING CUTANEOUS LEISHMANIASIS IN GUATEMALA [J].

NAVIN, TR ;

ARANA, BA ;

ARANA, FE ;

BERMAN, JD ;

CHAJON, JF .

JOURNAL OF INFECTIOUS DISEASES, 1992, 165 (03) :528-534