5-FLUORO-SUBSTITUTED PYRAZOLES

被引：8

作者：

BARGAMOVA, MD

MOTSISHKITE, SM

KNUNYANTS, IL

机构：

[1] A. N. Nesmeyanov Institute of Heteroorganic Compounds, Academy of Sciences of the USSR, Moscow

来源：

BULLETIN OF THE ACADEMY OF SCIENCES OF THE USSR DIVISION OF CHEMICAL SCIENCE | 1990年 / 39卷 / 11期

关键词：

D O I：

10.1007/BF00958848

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A preparative method was developed for the synthesis of 5-fluoro-substituted pyrazoles by the reaction of fluoroolefins with substituted hydrazines in the presence of triethylamine. The fluorine atom at the C5 position of the pyrazoles obtained is readily substituted by O-, N-, and S-nucleophiles with the formation of 5-alkoxy-, amino-, mercapto-substituted fluoroalkylpyrazoles.

引用

页码：2338 / 2344

页数：7

共 8 条

[1]

BARGAMOVA MD, 1986, 5TH ALL UN C FLUOR C

[2]

BARGAMOVA MD, 1989, Patent No. 1456419

[3] SYNTHESIS OF CYCLIC AMINIMINES WITH PERFLUOROALKYL GROUPS [J].