APPLICATION OF ORGANOLITHIUM AND RELATED REAGENTS IN SYNTHESIS .13. SYNTHETIC STRATEGIES BASED ON AROMATIC METALATION - A CONCISE REGIOSPECIFIC CONVERSION OF BENZOIC-ACIDS INTO 4-HYDROXY-1-ARYLNAPHTHALENES

被引：22

作者：

EPSZTAJN, J

JOZWIAK, A

SZCZESNIAK, AK

机构：

来源：

TETRAHEDRON | 1993年 / 49卷 / 04期

关键词：

D O I：

10.1016/S0040-4020(01)80334-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the 3-unsubstituted phthalides (S) and their conversion into 1-hydroxy-1-arylphthalans (8), very useful precursors of isobenzofurans (10) and subsequent cycloaddition of them to dimethyl acetylenedicarboxylate as a way of regiospecific transformation of benzoic acids into dimethyl 4-hydroxy-1-(2-methoxyphenyl)naphthalene-2,3-dicarboxylates (12) (biaryls highly substituted around the axis), is described.

引用

页码：929 / 938

页数：10

共 27 条

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