COMPARISON OF RISK-FACTORS FOR HEPATITIS-C AND HEPATITIS-B VIRUS-INFECTION IN HOMOSEXUAL MEN

被引：116

作者：

OSMOND, DH

CHARLEBOIS, E

SHEPPARD, HW

PAGE, K

WINKELSTEIN, W

MOSS, AR

REINGOLD, A

机构：

[1] UNIV CALIF SAN FRANCISCO, DEPT EPIDEMIOL & BIOSTAT, SAN FRANCISCO, CA 94143 USA

[2] CALIF DEPT HLTH SERV, VIRAL & RICKETTSIAL DIS LAB, SACRAMENTO, CA USA

[3] UNIV CALIF BERKELEY, SCH PUBL HLTH, BERKELEY, CA 94720 USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1993年 / 167卷 / 01期

关键词：

D O I：

10.1093/infdis/167.1.66

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Serum samples from 735 homosexual or bisexual men were tested for antibodies to hepatitis C virus (HCV) and serologic markers of hepatitis B virus (HBV), and risk factors for each infection were compared. Thirty-four (4.6%) were confirmed HCV-positive compared with 81% positive for one or more H BV serologic marker(s). History of intravenous drug use (IVDU) and blood transfusion were significantly associated with HCV positivity (odds ratio [OR] = 14.3 and 4.4, respectively), but neither was significantly associated with HBV positivity. Sexual behavior was significantly associated with infection with both viruses. When IVDU and blood transfusion were controlled for, HCV infection was marginally associated with >50 sex partners/year (OR 2.1), >25 oral receptive partners (OR = 2.4), and >25 anal receptive partners (OR = 1.9). HBV infection was more strongly associated with the same variables. HCV infection is uncommon in homosexual men and IVDU is the primary route of transmission, but sexual transmission also occurs, albeit infrequently.

引用

页码：66 / 71

页数：6

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