ASPECTS OF THE THROMBOXANE RECEPTOR SYSTEM

被引：26

作者：

ARMSTRONG, RA

WILSON, NH

机构：

[1] University of Edinburgh, Department of Pharmacology, Edinburgh, EH8 9JZ Scotland

来源：

GENERAL PHARMACOLOGY | 1995年 / 26卷 / 03期

关键词：

THROMBOXANE (TP) RECEPTORS; EPI PROSTOGLANDINS; MOLECULAR BIOLOGY;

D O I：

10.1016/0306-3623(94)00183-N

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. The aim of this review is to establish what is known about the thromboxane (TP) receptor, and to identify where future research is headed. In addition, the impact of the recent advances at the molecular level on resolving pharmacological controversies, such as possible subtypes of the TP receptor, is discussed and what molecular information is known about the TP receptor presented. 2. The clinical status of TP receptor anatagonists is considered particularly in relation to the potential role of epi prostaglandins. 3. Basic information about TP agonists, antagonists and signal transduction pathways is also given.

引用

收藏

页码：463 / 472

页数：10

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