THE USE OF ORTHO-NITROARYLACETONITRILES AS CARBON ACID PARTICIPANTS IN THE MITSUNOBU REACTION

被引：30

作者：

MACOR, JE

WEHNER, JM

机构：

[1] Department of Medicinal Chemistry Central Research Division, Pfizer Inc, Groton

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 49期

关键词：

D O I：

10.1016/0040-4039(91)80474-K

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of o-nitroarylacetonitriles as carbon acids in the Mitsunobu reaction is discussed as a method of carbon-carbon bond formation. This reaction represents a rare example of a carbon acid participating in a Mitsunobu reaction.

引用

页码：7195 / 7198

页数：4

共 5 条

[1] MACOR JE, 1990, HETEROCYCLES, V31, P805
[2] 3-(1,2,5,6-TETRAHYDROPYRID-4-YL)PYRROLO[3,2-B]PYRID-5-ONE - A POTENT AND SELECTIVE SEROTONIN (5-HT1B) AGONIST AND ROTATIONALLY RESTRICTED PHENOLIC ANALOG OF 5-METHOXY-3-(1,2,5,6-TETRAHYDROPYRID-4-YL)INDOLE
MACOR, JE
BURKHART, CA
HEYM, JH
IVES, JL
LEBEL, LA
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NIELSEN, JA
RYAN, K
SCHULZ, DW
TORGERSEN, LK
KOE, BK
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (08) : 2087 - 2093
[3] MAKOSZA M, 1988, LIEBIGS ANN CHEM, P203
[4] THE USE OF DIETHYL AZODICARBOXYLATE AND TRIPHENYLPHOSPHINE IN SYNTHESIS AND TRANSFORMATION OF NATURAL-PRODUCTS
MITSUNOBU, O
[J]. SYNTHESIS-STUTTGART, 1981, (01): : 1 - 28
[5] WADA M, 1972, TETRAHEDRON LETT, P1279

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