THE VALUE OF HYSTEROSCOPY IN ELDERLY WOMEN PRIOR TO INVITRO FERTILIZATION EMBRYO TRANSFER (IVF-ET) - A COMPARATIVE-STUDY

被引:28
作者
DICKER, D [1 ]
GOLDMAN, JA [1 ]
ASHKENAZI, J [1 ]
FELDBERG, D [1 ]
DEKEL, A [1 ]
机构
[1] HASHARON HOSP,GOLDA MEIR MED CTR,DEPT OBSTET & GYNECOL,SHERMAN FERTIL INST,IL-49372 PETAH TIQWA,ISRAEL
来源
JOURNAL OF IN VITRO FERTILIZATION AND EMBRYO TRANSFER | 1990年 / 7卷 / 05期
关键词
elderly women; hysteroscopy; in vitro fertilization; uterine factor;
D O I
10.1007/BF01129532
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Two hundred eighty-four hysteroscopies were performed in 312 (91%) candidates for in vitro fertilization and embryo transfer (IVF-ET) who were divided into two groups. Group I consisted of elderly women over 40 years, and group II of women below this age. Although visualization revealed uterine abnormalities in 29.9% of all patients, abnormal findings were significantly increased in the former group in comparison to the latter (P<0.001). This difference was attributed mainly to uterine rather than cervical pathology. Furthermore, in elderly women agerelated uterine pathology such as submucous myomata, endometrial hyperplasia, and polyps were more prominent, while in younger patients other uterine lesions such as adhesions and tubal ostia occlusion were more common. Moreover, treatment prior to IVF-ET resulted in 7 clinical pregnancies (8.9%) in group I and in 41 clinical pregnancies (19.9%) in group II, all of which failed in one to three cycles previously. It seems that hysteroscopic evaluation may reduce the IVF-ET failure rate due to intrauterine abnormalities in elderly as well as young patients, thus it becomes an absolute prerequisite for all patients scheduled for an IVF program. © 1990 Plenum Publishing Corporation.
引用
收藏
页码:267 / 270
页数:4
相关论文
共 9 条
[1]  
March C.M., Hysteroscopy as an aid to diagnosis in female infertility, Clin Obstet Gynecol, 26, pp. 302-309, (1983)
[2]  
Valle R.F., Hysteroscopy in the evaluation of female infertility, Am J Obstet Gynecol, 137, pp. 425-431, (1980)
[3]  
Buttram V.C., Reiter R.C., Uterine leiomyomata etiology, symptomatology and management, Fertil Steril, 36, pp. 433-440, (1981)
[4]  
Gindoff P.R., Jewelewicz R., Reproductive potential in the older woman, Fertil Steril, 46, pp. 989-1001, (1986)
[5]  
Gosden R.G., Maternal age: A major factor affecting the prospects and outcome of pregnancy, Ann NY Acad Sci, 442, pp. 45-57, (1984)
[6]  
Sweeney W.J., Accuracy of preoperative hysterosalpingograms, Obstet Gynecol, 2, pp. 640-645, (1958)
[7]  
Asherman J.G., Traumatic intrauterine adhesions, Br J Obstet Gynecol, 57, pp. 892-897, (1950)
[8]  
Zondek B., Rozin S., Filling defects in the hysterogram simulating I.U. synechiae which disappear after denervation, Am J Obstet Gynecol, 88, pp. 123-129, (1964)
[9]  
Hamou J., Microhysteroscopy, Clin Obstet Gynecol, 26, pp. 277-281, (1983)