NON-DECARBOXYLATIVE 1,3-DIPOLAR CYCLOADDITIONS OF IMINES OF ALPHA-AMINO-ACIDS AS A ROUTE TO PROLINE DERIVATIVES

被引：38

作者：

ALY, MF ^{[1
]}

YOUNES, MI ^{[1
]}

METWALLY, SAM ^{[1
]}

机构：

[1] UAE UNIV,FAC SCI,DEPT CHEM,AL AIN,U ARAB EMIRATES

来源：

TETRAHEDRON | 1994年 / 50卷 / 10期

关键词：

D O I：

10.1016/S0040-4020(01)81114-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha-Amino acids react with aryl aldehydes in the presence of N-substituted maleimides to yield stereospecific cycloadducts (3a,b) with dimethyl fumarate to give isometric mixtures of (4a-i) and (5a-i). The relatively low yield in the case of dimethyl fumarate is presumably due to the steric interaction between the dipolarophile and the substituents at both ends of the dipole.

引用

页码：3159 / 3168

页数：10

共 15 条

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