GESTATIONAL ZINC DEPRIVATION IN MICE - PERSISTENCE OF IMMUNODEFICIENCY FOR 3 GENERATIONS

被引：164

作者：

BEACH, RS ^{[1
]}

GERSHWIN, ME ^{[1
]}

HURLEY, LS ^{[1
]}

机构：

[1] UNIV CALIF DAVIS, DEPT NUTR, DAVIS, CA 95616 USA

来源：

SCIENCE | 1982年 / 218卷 / 4571期

关键词：

D O I：

10.1126/science.7123244

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Pregnant Swiss Webster mice were fed a diet moderately deficient in zinc from day 7 of gestation until parturition. Offspring of these mice showed depressed immune function through 6 mo. of age. The 2nd and 3rd filial generations, all of which were fed only the normal control diet, continued to manifest reduced immunocompetence, although not to the same degree as in the 1st generation.

引用

页码：469 / 471

页数：3

共 29 条

[1]

AREF GH, 1970, J TROP MED HYG, V73, P186

[2]

BEACH RS, 1982, J IMMUNOL, V128, P308

[3] IMPAIRED IMMUNOLOGICAL ONTOGENY IN POSTNATAL ZINC DEPRIVATION [J].