TUMOR SUPPRESSOR GENES

被引：13

作者：

COWELL, JK

机构：

[1] ICRF Oncology Group, Institute of Child Health, London

来源：

ANNALS OF ONCOLOGY | 1992年 / 3卷 / 09期

关键词：

D O I：

10.1093/oxfordjournals.annonc.a058319

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Genes responsible for the hereditary predisposition to a variety of human cancers have now been isolated. Their function seems to be part of complex signalling pathways involved in the control of cellular differentiation and the cell cycle. The presence of a single copy of these genes appears to be sufficient to ensure normal development, i.e. prevents tumorigenesis, and has earned them the name-tumour suppressor genes.

引用

页码：693 / 698

页数：6

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