ENVIRONMENTAL-REGULATION OF VIRULENCE FACTORS IN BORDETELLA SPECIES

被引：21

作者：

SCARLATO, V

ARICO, B

DOMENIGHINI, M

RAPPUOLI, R

机构：

[1] Immunobiological Research Institute Siena (I.R.I.S.), Siena, 53100

来源：

BIOESSAYS | 1993年 / 15卷 / 02期

关键词：

D O I：

10.1002/bies.950150205

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many bacteria respond in a coordinate manner to environmental changes. External stimuli, sensed by receptors, are transduced to regulatory proteins which participate in well defined pathways of gene expression by varying their structure and mode of action. The network of environmental signal transduction is responsible for a fine and continuous communication between the host and the pathogenic bacteria. As a result, the gene expression machinery of the pathogen is modified continuously, in order to establish the optimal conditions for bacterial survival and multiplication.

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页码：99 / 104

页数：6

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