DEMENTIA - DIAGNOSIS AND EVALUATION

被引:41
作者
FLEMING, KC [1 ]
ADAMS, AC [1 ]
PETERSEN, RC [1 ]
机构
[1] MAYO CLIN & MAYO FDN,DEPT NEUROL,ROCHESTER,MN 55905
关键词
D O I
10.4065/70.11.1093
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To describe an approach to the diagnosis of dementia based on effective assessment methods. Design: We reviewed the literature and summarized the available diagnostic and prognostic studies of dementia that may be useful to the primary-care physician. Results: Although controversy exists about certain aspects of the diagnostic workup, exclusion of potentially reversible causes of dementia is essential, Laboratory studies (for example, for detection of underlying metabolic abnormalities) and neuroimaging of the brain may be useful, The pattern of onset and the temporal course of the disease may suggest a cause and help direct the investigation, Functional losses can substantially impair the patient's ability to live independently. Conclusion: Dementia can be mistakenly considered as part of the normal aging process, and diagnosis necessitates a thorough, although not exhaustive, approach, Early identification of dementing illnesses improves the outcome for reversible disease and may also enhance the management of incurable dementias.
引用
收藏
页码:1093 / 1107
页数:15
相关论文
共 97 条
[1]   THE PREVALENCE OF DEMENTIA IS CHANGING OVER TIME IN ROCHESTER, MINNESOTA [J].
BEARD, CM ;
KOKMEN, E ;
OBRIEN, PC ;
KURLAND, LT .
NEUROLOGY, 1995, 45 (01) :75-79
[2]   THE ROLE OF LUMBAR PUNCTURE IN THE EVALUATION OF DEMENTIA - THE DURHAM-VETERANS-ADMINISTRATION DUKE-UNIVERSITY STUDY [J].
BECKER, PM ;
FEUSSNER, JR ;
MULROW, CD ;
WILLIAMS, BC ;
VOKATY, KA .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1985, 33 (06) :392-396
[3]   PREDICTORS OF MORTALITY AND INSTITUTIONALIZATION IN ALZHEIMER-DISEASE PATIENTS 1 YEAR AFTER-DISCHARGE FROM AN ALZHEIMER DEMENTIA UNIT [J].
BIANCHETTI, A ;
SCURATTI, A ;
ZANETTI, O ;
BINETTI, G ;
FRISONI, GB ;
MAGNI, E ;
TRABUCCHI, M .
DEMENTIA, 1995, 6 (02) :108-112
[4]   AGE-SPECIFIC NORMS FOR THE MINI-MENTAL STATE EXAM [J].
BLEECKER, ML ;
BOLLAWILSON, K ;
KAWAS, C ;
AGNEW, J .
NEUROLOGY, 1988, 38 (10) :1565-1568
[5]   FACTORS AFFECTING COURSE AND SURVIVAL IN ALZHEIMERS-DISEASE - A 9-YEAR LONGITUDINAL-STUDY [J].
BRACCO, L ;
GALLATO, R ;
GRIGOLETTO, F ;
LIPPI, A ;
LEPORE, V ;
BINO, G ;
LAZZARO, MP ;
CARELLA, F ;
PICCOLO, T ;
POZZILLI, C ;
GIOMETTO, B ;
AMADUCCI, L .
ARCHIVES OF NEUROLOGY, 1994, 51 (12) :1213-1219
[6]   COGNITIVE IMPAIRMENT FOLLOWING CLOSED HEAD-INJURY [J].
CAPRUSO, DX ;
LEVIN, HS .
NEUROLOGIC CLINICS, 1992, 10 (04) :879-893
[7]  
Caselli RJ, 1995, NEUROLOGIST, V1, P1
[8]   THE REVERSIBLE DEMENTIAS - DO THEY REVERSE [J].
CLARFIELD, AM .
ANNALS OF INTERNAL MEDICINE, 1988, 109 (06) :476-486
[9]  
CLARFIELD AM, 1989, JAMA-J AM MED ASSOC, V262, P2592
[10]  
CLARFIELD AM, 1990, J FAM PRACTICE, V31, P405