ONLINE PROCESSING OF PHARMACEUTICAL MATERIALS USING IN-SITU X-RAY-DIFFRACTION

被引：20

作者：

MACCALMAN, ML

ROBERTS, KJ

KERR, C

HENDRIKSEN, B

机构：

[1] UNIV STRATHCLYDE,DEPT PURE & APPL CHEM,GLASGOW G1 1XL,LANARK,SCOTLAND

[2] GLASGOW COMP SERV,GLASGOW G1 6DP,LANARK,SCOTLAND

[3] LILLY RES CTR LTD,WINDLESHAM GU20 6PH,SURREY,ENGLAND

[4] DRAL,DARESBURY LAB,WARRINGTON WA4 4AD,CHESHIRE,ENGLAND

来源：

JOURNAL OF APPLIED CRYSTALLOGRAPHY | 1995年 / 28卷

关键词：

D O I：

10.1107/S0021889895006765

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel on-line processing cell for examination of the polymorphic forms of pharmaceutical materials using in situ X-ray diffraction is presented. The utility of this technique is demonstrated through an examination of the temperature-dependent polymorphic behaviour of an antibiotic material following recrystallization.

引用

页码：620 / 622

页数：3

共 8 条

[1]

AULTON ME, 1988, PHARMACEUTICS SCI DO

[2] USING INSITU SYNCHROTRON RADIATION POWDER DIFFRACTION TO CHARACTERIZE GROWTH-RELATED STRUCTURAL POLYMORPHIC PHASE-TRANSFORMATIONS IN CIS-9-OMEGA-OCTADECENOIC ACID [J].