DRUG-DEPENDENCE WITH ESTROGEN REPLACEMENT THERAPY

被引：18

作者：

BEWLEY, S ^{[1
]}

BEWLEY, TH ^{[1
]}

机构：

[1] ST GEORGE HOSP,SCH MED,DEPT ADDICT BEHAV,LONDON SW17,ENGLAND

来源：

LANCET | 1992年 / 339卷 / 8788期

关键词：

D O I：

10.1016/0140-6736(92)91344-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Dependence on some drugs can be hard to recognise. Hormone replacement therapy (HRT) has been widely prescribed only in the past two decades, and the indications for treatment and the risk/benefit ratio are still disputed. Oestrogens are psychoactive: they lift mood, can be given by injection, and their use has powerful psychological effects. Reports of women with supraphysiological oestradiol concentrations may represent tolerance and withdrawal. Dependence on substances occurring naturally in the body has been reported before. We propose that HRT dependence occurs.

引用

页码：290 / 291

页数：2

共 20 条

[1]

APPLEBY L, 1991, PROGR OBSTETRICS GYN, V9, P289

[2]

BRINCAT M, 1984, LANCET, V1, P16

[3]

BROWER KJ, 1991, BRIT J ADDICT, V86, P759

[4]

CAMPBELL S, 1977, CLIN OBSTET GYNAECOL, V4, P31

[5] SYMPTOMS OF ESTROGEN DEFICIENCY ASSOCIATED WITH SUPRAPHYSIOLOGICAL PLASMA ESTRADIOL CONCENTRATIONS IN WOMEN WITH ESTRADIOL IMPLANTS [J].

GANGAR, K ;

CUST, M ;

WHITEHEAD, MI .

BRITISH MEDICAL JOURNAL, 1989, 299 (6699) :601-602

[6] HORMONE IMPLANTS AND TACHYPHYLAXIS [J].

GANGAR, K ;

WHITEHEAD, MI .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1991, 98 (06) :607-608

[7] PROLONGED ENDOMETRIAL STIMULATION ASSOCIATED WITH ESTRADIOL IMPLANTS [J].

GANGAR, KF ;

FRASER, D ;

WHITEHEAD, MI ;

CUST, MP .

BRITISH MEDICAL JOURNAL, 1990, 300 (6722) :436-438

[8] HORMONE IMPLANTS AND TACHYPHYLAXIS [J].

GARNETT, T ;

STUDD, JWW ;

HENDERSON, A ;

WATSON, N ;

SAVVAS, M ;

LEATHER, A .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1990, 97 (10) :917-921

[9]

GINSBURG J, 1991, BRIT MED J, V302, P1601

[10] BENZODIAZEPINES - PANACEA OR POISON [J].

LADER, M .

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 1981, 15 (01) :1-9

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