FLUORESCENCE PROPERTIES OF OXIDIZED HUMAN PLASMA LOW-DENSITY LIPOPROTEINS

被引：15

作者：

SINGH, S ^{[1
]}

SURI, R ^{[1
]}

AGRAWAL, CG ^{[1
]}

机构：

[1] K G MED COLL,DEPT MED,LUCKNOW,UTTAR PRADESH,INDIA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM | 1995年 / 1254卷 / 02期

关键词：

LDL; 2ND-DERIVATIVE FLUORESCENCE SPECTROSCOPY; PROTEIN CROSS-LINKAGE; 3-DIMENSIONAL FLUORESCENCE SPECTROSCOPY; LIPID OXIDATION;

D O I：

10.1016/0005-2760(94)00173-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Appearance of fluorescence emission between 380-550 nm (lambda exc 350-400 nm) in freshly prepared low-density lipoprotein from asymptomatic normolipemic human plasma revealed the presence of in vivo oxidative modification of its protein moiety. Low-density lipoprotein elicited seven fluorophores in three dimensional fluorescence spectrogram. Assignment of fluorescent chemical structures originating from oxidative modification of the protein moiety of low-density lipoprotein has been made with the help of second derivative fluorescence spectroscopy.

引用

页码：135 / 139

页数：5

共 34 条

[1] PRESENCE OF A MODIFIED LOW-DENSITY LIPOPROTEIN IN HUMANS [J].