THE IMPORTANCE OF GENOME ANALYSIS TO THE DRUG DISCOVERY PROCESS

被引：9

作者：

BROWNE, MJ

GLOGER, IS

HODGSON, JE

ROBINSON, JH

机构：

[1] Department of Molecular and Cellular Biology, Biotech (Europe), SmithKline Beecham Pharmaceuticals, Epsom, KT18 5XQ, Great Burgh, Yew Tree Bottom Road

来源：

MOLECULAR MEDICINE TODAY | 1995年 / 1卷 / 08期

关键词：

D O I：

10.1016/S1357-4310(95)93853-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The sequencing of partial human expressed genes and of microbial genomes is leading to the discovery of many new targets for drug discovery. As more targets become known, drugs can be designed that have greater selectivity than was possible using traditional pharmacological methods. The promise of the new approach is that drugs discovered in this way will be highly efficacious and will have a reduced tendency for unwanted side-effects.

引用

页码：373 / 377

页数：5

共 29 条

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