ENANTIOSELECTIVE SYNTHESIS OF HYDROXY ALPHA-AMINO-ACIDS - (-)-ERYTHRO-GAMMA-HYDROXYNORVALINES AND (-)-THREO-GAMMA-HYDROXYNORVALINES

被引：38

作者：

ARIZA, J ^{[1
]}

FONT, J ^{[1
]}

ORTUNO, RM ^{[1
]}

机构：

[1] UNIV AUTONOMA BARCELONA,DEPT QUIM,UNITAT QUIM ORGAN,E-08193 BARCELONA,SPAIN

来源：

TETRAHEDRON | 1990年 / 46卷 / 06期

关键词：

D O I：

10.1016/S0040-4020(01)89761-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The amino acids (-)-erythro- and (-)-threo-γ-hydroxynorvaline have been synthesized from D-ribonolactone, 6, as single chiral precursor. Moreover, β-hydrox-αazido- γ-valerolactones 12a and 12b have been also prepared from 6 in two different alternative ways. These compounds afford β,γ-dihydroxy-α -amino acids 18a and 18b with Darabino and D-ribo configuration, respectively. © 1990.

引用

页码：1931 / 1942

页数：12

共 21 条

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