PROPRANOLOL - POOLED MICHAELIS-MENTEN PARAMETERS AND THE EFFECT OF INPUT RATE ON BIOAVAILABILITY

被引：50

作者：

WAGNER, JG ^{[1
]}

机构：

[1] UNIV MICHIGAN,COLL PHARM,ANN ARBOR,MI 48109

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 1985年 / 37卷 / 05期

关键词：

D O I：

10.1038/clpt.1985.76

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：481 / 487

页数：7

共 13 条

[1] COMPARATIVE ORAL BIOAVAILABILITY OF CONVENTIONAL PROPRANOLOL TABLETS AND A NEW CONTROLLED ABSORPTION PROPRANOLOL CAPSULE [J].

BOTTINI, PB ;

CAULFIELD, EM ;

DEVANE, JG ;

GEOGHEGAN, EJ ;

PANOZ, DE .

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1983, 9 (08) :1475-1493

[2] STUDY OF FACTORS INFLUENCING DRUG DISPOSITION IN CHRONIC LIVER-DISEASE, USING MODEL DRUG (+)-PROPRANOLOL [J].

BRANCH, RA ;

JAMES, J ;

READ, AE .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1976, 3 (02) :243-249

[3]

DVORNIK D, 1982, CURR THER RES CLIN E, V32, P214

[4]

GARG DC, 1984, CLIN PHARMACOL THER, V35, P242

[5]

OHASHI K, 1984, ARZNEIMITTEL-FORSCH, V34-1, P507

[6] STEADY-STATE PLASMA-CONCENTRATIONS AS A FUNCTION OF THE ABSORPTION RATE AND DOSING INTERVAL FOR DRUGS EXHIBITING CONCENTRATION-DEPENDENT CLEARANCE - CONSEQUENCES FOR PHENYTOIN THERAPY [J].

SAWCHUK, RJ ;

RECTOR, TS .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1979, 7 (06) :543-555

[7] QUANTITATIVE POOLING OF MICHAELIS-MENTEN EQUATIONS IN MODELS WITH PARALLEL METABOLITE FORMATION PATHS [J].

SEDMAN, AJ ;

WAGNER, JG .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1974, 2 (02) :149-160

[8] DOSE-DEPENDENT ELIMINATION OF PROPRANOLOL AND ITS MAJOR METABOLITES IN HUMANS [J].

SILBER, BM ;

HOLFORD, NHG ;

RIEGELMAN, S .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1983, 72 (07) :725-732

[9]

WAGNER JG, 1984, DRUG METAB DISPOS, V12, P385

[10] PREDICTABILITY OF VERAPAMIL STEADY-STATE PLASMA-LEVELS FROM SINGLE-DOSE DATA EXPLAINED [J].

WAGNER, JG .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1984, 36 (01) :1-4

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