CHAIN DYNAMICS IN POLY(AMIDO AMINE) DENDRIMERS - A STUDY OF H-2 NMR RELAXATION PARAMETERS

被引:83
作者
MELTZER, AD
TIRRELL, DA
JONES, AA
INGLEFIELD, PT
机构
[1] UNIV MASSACHUSETTS,DEPT POLYMER SCI & ENGN,AMHERST,MA 01003
[2] CLARK UNIV,DEPT CHEM,JEPPSON LAB,WORCESTER,MA 01610
关键词
D O I
10.1021/ma00044a014
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
H-2 NMR relaxation measurements were used in an extensive study of chain mobility in poly(amido amine) (PAMAM) dendrimers as a function of molecular weight and position along the chain. For H-2 labels in the terminal generation, the spin-lattice relaxation times (T1) were found to decrease as the number of chain termini increased from 3 (T1 = 30 +/- 3 ms, at 46.0 MHz) to 384 (T1 = 7.6 +/- 0.7 ms, at 46.0 MHz) and were smaller than the T1 observed when the polymers were labeled in the interior. The values of T1 determined at lower field strength (4.7 T) were lower than those at higher field strength (7.05 T). By using the spin-spin relaxation time (T2) as a second variable, consistent correlation times (tau) were obtained at the two field strengths upon application of Schaefer's log-chi-2 distribution function. No dependence of tau on position along the chain was observed when the label was located in the interior repeating units of PAMAM dendrimers of constant molecular weight. No evidence of radial gradients was found. The data are interpreted in terms of alternative theoretical treatments of dendritic macromolecules.
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页码:4549 / 4552
页数:4
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