SEQUENCE COMPARISON OF ECHOVIRUS TYPE-30 ISOLATES TO OTHER ENTEROVIRUSES IN THE 5'NONCODING REGION

被引：29

作者：

DIEDRICH, S

DRIESEL, G

SCHREIER, E

机构：

[1] Robert Koch-Institute, National Reference Center for Poliomyelitis and Enteroviruses, Berlin

来源：

JOURNAL OF MEDICAL VIROLOGY | 1995年 / 46卷 / 02期

关键词：

ECHOVIRUS; ENTEROVIRUS; PCR; SEQUENCING;

D O I：

10.1002/jmv.1890460212

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The genetic relationship between echovirus type 30 (E30) isolates were characterised by means of amplification of a part of the 5'noncoding region by polymerase chain reaction and direct sequencing. Later, the E30 sequences were compared with other enteroviruses. Homology between recent clinical E30 isolates from different years exceeds 98% at the nucleotide level. Comparing the E30 sequence with other enteroviruses, homology varied between 68% (coxsackievirus A24) and 93% (coxsackievirus B3). E30 appeared to have coxsackie B-like characteristics in this genomic part. It is considered that E30 and coxsackie B viruses belong to the same enterovirus subgroup. (C) 1995 Wiley-Liss, Inc.

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页码：148 / 152

页数：5

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