A CLINICOPATHOLOGICAL STUDY ON INTRAHEPATIC CHOLESTEROL GALLSTONES

被引：9

作者：

AKIYAMA, T

NAGAKAWA, T

KANNO, M

OHTA, T

UENO, K

HIGASHINO, Y

KONISHI, I

MIYAZAKI, I

UOGISHI, M

SODANI, H

机构：

[1] The Second Department of Surgery, School of Medicine, Kanazawa University, Kanazawa

[2] Department of Gastroenterology, Keiju General Hospital, Ishikawa, 920, Takaramachi 13-1, Kanazawa, Ishikawa

来源：

JAPANESE JOURNAL OF SURGERY | 1990年 / 20卷 / 05期

关键词：

cholesterol crystal; cholesterol gallstone; intrahepatic gallstone;

D O I：

10.1007/BF02471009

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

In order to clarify the pathogenesis and process of the formation of intrahepatic cholesterol gallstones, we examined the clinical features, cholangiograms and pathological findings of eight patients with intrahepatic cholesterol gallstones. When examining the clinical features, one patient was found to have developed intrahepatic cholesterol gallstones 3 years after a complete lithotomy. The cholangiograms of two patients revealed small gallstones in the peripheral bile ducts of the lateral segment of the liver, and these bile ducts showed localized cystic dilatation and were tightly filled with gallstones. Conversely, their other bile ducts which contained no gallstones showed an entirely normal cholangiogram. Pathologically, these two cases showed mild chronic cholangitis, and cholesterol crystals in the peripheral bile ducts. The other six cases showed moderate or severe dilatation of the bile duct and severe chronic proliferative cholangitis. From the above results, we proposed the following theory to explain the pathogenesis and process of the formation of intrahepatic cholesterol stones: The cholesterol crystals in the peripheral intrahepatic bile ducts may be a primitive form of intrahepatic cholesterol gallstones, and the formation of intrahepatic cholesterol gallstones may precede and cause such deformities of the bile ducts as strictures or dilatations. © 1990 The Japan Surgical Society.

引用

页码：530 / 536

页数：7

共 9 条

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