METABOLIC DYNAMICS IN THE HUMAN RED-CELL .4. DATA PREDICTION AND SOME MODEL COMPUTATIONS

被引：41

作者：

JOSHI, A ^{[1
]}

PALSSON, BO ^{[1
]}

机构：

[1] UNIV MICHIGAN,DEPT CHEM ENGN,ANN ARBOR,MI 48109

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1990年 / 142卷 / 01期

关键词：

D O I：

10.1016/S0022-5193(05)80013-X

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The biochemical information on the basic cellular determinants of the human red cell has been compiled into a comprehensive model of the red cell metabolic machinery. This model gives a consistent interpretation-both qualitative and quantitative-of the experimental findings. The predicted steady states and the dynamic states of the model are compared with the experimental findings, and the utility of this model is demonstrated. © 1990 Academic Press Limited All rights reserved.

引用

页码：69 / 85

页数：17

共 34 条

[1] ENERGY CHARGE OF ADENYLATE POOL AS A REGULATORY PARAMETER . INTERACTION WITH FEEDBACK MODIFIERS [J].

ATKINSON, DE .

BIOCHEMISTRY, 1968, 7 (11) :4030-&

[2]

Beutler E, 1975, Glutathione in red cell metabolism, A manual of biochemical methods, V2nd, P112

[3]

BEUTLER E, 1973, HUMAN RED CELL IN VI, P189

[4]

CONNEY DO, 1976, BIOMEDICAL ENG PRINC

[5]

DOEDEL E, 1985, AUTO 80 SOFTWARE CON

[6] DEPENDENCY OF SYNTHESIS OF 2,3-DIPHOSPHOGLYCERATE IN HUMAN ERYTHROCYTES ON CONCENTRATION OF ADP [J].

DUHM, J ;

DEUTICKE, B ;

GERLACH, E .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1969, 306 (04) :329-&

[7]

DUHM MJ, 1973, HUMAN RED CELL IN VI, P111

[8] PHOSPHORIBOSYLPYROPHOSPHATE IN MAN - BIOCHEMICAL AND CLINICAL SIGNIFICANCE [J].

FOX, IH ;

KELLEY, WN .

ANNALS OF INTERNAL MEDICINE, 1971, 74 (03) :424-+

[9] CHLORIDE AND HYDROGEN ION DISTRIBUTION BETWEEN HUMAN RED CELLS AND PLASMA [J].

FUNDER, J ;

WIETH, JO .

ACTA PHYSIOLOGICA SCANDINAVICA, 1966, 68 (02) :234-&

[10]

GERBER G, 1975, 7 INT S STRUKT FUNKT, P272

← 1 2 3 4 →