CHROMOSOME MAPPING OF HUMAN (ZNF147) AND MOUSE GENES FOR ESTROGEN-RESPONSIVE FINGER PROTEIN (EFP), A MEMBER OF THE RING FINGER FAMILY

被引：13

作者：

INOUE, S

ORIMO, A

MATSUDA, Y

INAZAWA, J

EMI, M

NAKAMURA, Y

HORI, TA

MURAMATSU, M

机构：

[1] SAITAMA MED SCH,DEPT BIOCHEM,MOROYAMA,SAITAMA 35004,JAPAN

[2] NATL INST RADIOL SCI,DIV GENET,INAGE KU,CHIBA 263,JAPAN

[3] KYOTO PREFECTURAL UNIV MED,DEPT HYG,KAMIKYO KU,KYOTO 602,JAPAN

[4] CANC INST,DEPT BIOCHEM,TOKYO 170,JAPAN

来源：

GENOMICS | 1995年 / 25卷 / 02期

关键词：

D O I：

10.1016/0888-7543(95)80064-S

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have previously identified an estrogen-responsive gene, efp (estrogen-responsive finger protein), that encodes a putative zinc finger protein (Proc. Noti. Acad. Sci. USA 90: 11117-11121, 1993). The efp protein has a RING finger, a variant type of zinc finger motif, B1 box, and B2 box, each having a pair of zinc fingers, present in a family of apparent DNA-binding proteins. Some members of this family have transformation capabilities when found in chromosomal translocations, Chromosome mapping of the efp gene by fluorescence in situ hybridization reveals that human EFP (ZNF147) is located at 17q23.1 and that mouse Efp is located at 11C. These results provide additional evidence that the mouse 11C region displays conserved synteny with the 17q23.1 region of the human genome. (C) 1995 Academic Press, Inc.

引用

页码：581 / 583

页数：3

共 16 条

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