REGIONAL MAPPING OF HEXOKINASE-1 WITHIN THE SHORT ARM OF CHROMOSOME-10

被引：7

作者：

DALLAPICCOLA, B

NOVELLI, G

MICARA, G

DELAROCHE, I

MORICPETROVIC, S

MAGNANI, M

机构：

[1] UNIV URBINO, IST CHIM BIOL, I-61029 URBINO, ITALY

[2] INST MENTAL HLTH, CTR MED GENET, BEOGRAD, YUGOSLAVIA

来源：

HUMAN HEREDITY | 1984年 / 34卷 / 03期

关键词：

D O I：

10.1159/000153453

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Hexokinase-1 (HK1) activity was determined in red cells of 5 patients with partial duplications of chromosome 10, all of which involved the 10p region. In 4 patients the level of HK1 activity were higher than the mean activity of controls, strongly indicating a triplex dosage effect. The most likely regional assignment for HK1 would appear to be 10p11.2.

引用

页码：156 / 160

页数：5

共 20 条

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