H-1-NMR STUDY OF GLYCOPEPTIDES WITH THE TRIPLET SEQUENCE ASN-GLY-SER

被引：12

作者：

ISHII, H

INOUE, Y

CHUJO, R

机构：

[1] Tokyo Inst of Technology, Dep of, Polymer Chemistry, Tokyo, Jpn, Tokyo Inst of Technology, Dep of Polymer Chemistry, Tokyo, Jpn

来源：

POLYMER JOURNAL | 1985年 / 17卷 / 05期

关键词：

CONFORMATION - GLYCOPEPTIDES - NMR - TRIPLET SEQUENCE;

D O I：

10.1295/polymj.17.693

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The conformation and intramolecular interactions in solution were investigated for the glycopeptides, Boc-Asn(GlcNac)-OMe, Boc-Asn(GlcNAc)-Gly-OMe, and Boc-Asn(GlcNAc)-Gly-Ser-OMe with the aids of **1H NMR. There are no specific intramolecular interactions in glycopeptides and the hydrogen bond between the side chains of Asn and Ser was not found in Boc-Asn(GlcNAc)-Gly-Ser-OMe contrary to that in Boc-Asn-Gly-Ser-OMe. The side chain conformation of the triplet sequence is considerably affected by N-glycosylation.

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页码：693 / 700

页数：8

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