SELECTIVE ENE-YNE COUPLING-FUNCTIONALIZATION - A NEW STRATEGY IN CONSTRUCTING HETEROCYCLES

被引：29

作者：

WANG, Z ^{[1
]}

LU, XY ^{[1
]}

机构：

[1] CHINESE ACAD SCI,SHANGHAI INST ORGAN CHEM,SHANGHAI 200032,PEOPLES R CHINA

来源：

TETRAHEDRON | 1995年 / 51卷 / 09期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/0040-4020(95)00035-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fluorinated derivatives of 3-alkylidene-2(3H)-dihydrofuranone have been synthesized by sodium dithionite initiated tandem perfluoroalkylation-cyclization of allylic 2-alkynoates in fair to good yield and high stereoselectivity. Fluorinated 3-alkylidene-2(3H)-pyrrolidone derivatives were prepared similarly. A mechanistic rationale concerning the different radical steps and the differences between esters and amides was given.

引用

页码：2639 / 2658

页数：20

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