OCCURRENCE OF CERAMIDE DIGALACTOSIDE AS THE MAIN GLYCOSPHINGOLIPID IN THE MARINE SPONGE HALICHONDRIA-JAPONICA

被引：21

作者：

HAYASHI, A

NISHIMURA, Y

MATSUBARA, T

机构：

[1] Department of Chemistry, Faculty of Science and Technology, Kinki University, Higashiosaka, Kowakae

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1991年 / 1083卷 / 02期

关键词：

CERAMIDE DIGALACTOSIDE; CERAMIDE MONOHEXOSIDE; HYDROXY FATTY ACID; LONG-CHAIN BASE; BRANCHED; FABMS; (SPONGE); (H-JAPONICA);

D O I：

10.1016/0005-2760(91)90040-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The main glycosphingolipid of the sponge Halichondria japonica was isolated and its structure was determined to be ceramide digalactoside, Gal-alpha-1 --> 4Gal-beta-1 --> 1Cer, using FAB/MS, IR, H-1-NMR and chemical methods such as permethylation analysis and degradation techniques. The ceramide moiety was composed mainly of 4-hydroxy-iso-octadecasphinganine and 2-hydroxy-docosanoic acid. Interestingly, the branched long-chain bases were comprised of 70% total long-chain bases and 17.5% 4-hydroxy-anteiso-nonadecasphinganine. Ceramide monohexoside, consisting of galactosyl ceramide (81%) and glucosyl ceramide (19%), was also isolated as a minor component. The composition of the ceramide moiety was nearly the same as that of ceramide digalactoside.

引用

页码：179 / 186

页数：8

共 38 条

[1] GAS-LIQUID CHROMATOGRAPHY AND MASS SPECTROMETRY IN METHYLATION ANALYSIS OF POLYSACCHARIDES [J].