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ANTIGEN-BINDING SPECIFICITIES OF ANTIBODIES ARE PRIMARILY DETERMINED BY 7 RESIDUES OF VH

被引：63
作者：
OHNO, S
MORI, N
MATSUNAGA, T
机构：
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1985年 / 82卷 / 09期
关键词：
D O I：
10.1073/pnas.82.9.2945
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：2945 / 2949
页数：5
相关论文
共 25 条
  • [1] HEAVY-CHAIN VARIABLE REGION CONTRIBUTION TO THE NPB FAMILY OF ANTIBODIES - SOMATIC MUTATION EVIDENT IN A GAMMA-2A VARIABLE REGION
    BOTHWELL, ALM
    PASKIND, M
    RETH, M
    IMANISHIKARI, T
    RAJEWSKY, K
    BALTIMORE, D
    [J]. CELL, 1981, 24 (03) : 625 - 637
  • [2] SIMPLE DNA-SEQUENCES IN HOMOLOGOUS FLANKING REGIONS NEAR IMMUNOGLOBULIN VH GENES - A ROLE IN GENE INTERACTION
    COHEN, JB
    EFFRON, K
    RECHAVI, G
    BEN-NERIAH, Y
    ZAKUT, R
    GIVOL, D
    [J]. NUCLEIC ACIDS RESEARCH, 1982, 10 (11) : 3353 - 3370
  • [3] SOMATIC MUTATION IN A CULTURED MOUSE MYELOMA CELL AFFECTS ANTIGEN-BINDING
    COOK, WD
    RUDIKOFF, S
    GIUSTI, AM
    SCHARFF, MD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (04): : 1240 - 1244
  • [4] A SINGLE VH GENE SEGMENT ENCODES THE IMMUNE-RESPONSE TO PHOSPHORYLCHOLINE - SOMATIC MUTATION IS CORRELATED WITH THE CLASS OF THE ANTIBODY
    CREWS, S
    GRIFFIN, J
    HUANG, H
    CALAME, K
    HOOD, L
    [J]. CELL, 1981, 25 (01) : 59 - 66
  • [5] SOMATIC MUTATION OF THE T15 HEAVY-CHAIN GIVES RISE TO AN ANTIBODY WITH AUTOANTIBODY SPECIFICITY
    DIAMOND, B
    SCHARFF, MD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (18): : 5841 - 5844
  • [6] A NEW CLASSIFICATION OF MOUSE VH SEQUENCES
    DILDROP, R
    [J]. IMMUNOLOGY TODAY, 1984, 5 (04): : 85 - 86
  • [7] AN IMMUNOGLOBULIN HEAVY-CHAIN VARIABLE REGION GENE IS GENERATED FROM 3 SEGMENTS OF DNA - VH, D AND JH
    EARLY, P
    HUANG, H
    DAVIS, M
    CALAME, K
    HOOD, L
    [J]. CELL, 1980, 19 (04) : 981 - 992
  • [8] EILAT D, 1984, J IMMUNOL, V133, P489
  • [9] DIVERSITY OF GERM-LINE IMMUNOGLOBULIN-VH GENES
    GIVOL, D
    ZAKUT, R
    EFFRON, K
    RECHAVI, G
    RAM, D
    COHEN, JB
    [J]. NATURE, 1981, 292 (5822) : 426 - 430
  • [10] GOJOBORI T, 1985, P NATL ACAD SCI US, V82
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